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Table 1 Associations of TRIB3 expression levels with clinicopathological factors.

From: Tribbles homolog 3 denotes a poor prognosis in breast cancer and is involved in hypoxia response

Variable

n= 247a

Median

(*10-3 TRIB3/HPRT)

Interquartile range

(*10-3 TRIB3/HPRT)

P

Age (years)

    

< 50

58

8.6

36

 

≥50

189

6.6

26

0.456b

Menopausal status

    

Premenopausal

65

9.4

34

 

Postmenopausal

182

6.6

27

0.500b

Nodal category

    

Negative

100

9.0

31

 

< 4 nodes

79

4.7

18

 

≥4 nodes

39

16

46

0.057c

Tumor type

    

Ductal

146

8.6

35

 

Lobular

28

13

25

 

Other (mixed/unknown)

73

2.7

18

0.007c

Tumor size

    

pT1

61

5.2

28

 

pT2

135

7.1

34

 

pT3/4

47

6.9

22

0.616c

Histological grade

    

I

11

5.1

17

 

II

70

6.4

36

 

III

88

8.5

31

0.729c

Estrogen receptor (fmol/mg protein)

    

< 10

84

7.2

30

 

≥10

159

5.8

27

0.895b

Progestrone receptor (fmol/mg protein)

    

< 10

103

7.1

32

 

≥10

141

6.6

23

0.663b

  1. aDue to missing values, numbers do not always add up to 247.
  2. b P for Mann-Whitney U test.
  3. c P for Kruskal-Wallis test.
  4. HPRT, hypoxanthine-guanine phosphoribosyltransferase;