Figure 1
From: Tribbles homolog 3 denotes a poor prognosis in breast cancer and is involved in hypoxia response
TRIB3 expression is associated with poor prognosis in breast cancer. Patients where divided into three groups based on their TRIB3 mRNA levels; less than 33% (dotted line), 33% to 66% (dashed line) and more than 66% (solid line). Kaplan-Meier plots of (a) disease-free survival (DFS; P = 0.002) and (b) overall survival (OS; P < 0.001) in breast cancer patients (n = 274) and DFS (c) in patients with mastectomy without further radiotherapy (n = 67, P = 0.719) and (d) in patients that received postoperative radiotherapy (n = 179, P = 0.005).