Skip to main content
Figure 3 | Breast Cancer Research

Figure 3

From: The non-protein coding breast cancer susceptibility locus Mcs5a acts in a non-mammary cell-autonomous fashion through the immune system and modulates T-cell homeostasis and functions

Figure 3

Mcs5a modulates γδTCR+ T-cell homeostasis. Percentages of (a) CD4+, (b) CD8+, and (c) γδTCR+ T cells in the splenic CD3+ T-cell population from susceptible congenic control (n = 26), Mcs5a-resistant congenic (n = 26), Mcs5a1 susceptible congenic (n = 20), and Mcs5a2 susceptible congenic (n = 15) rats. The significantly different (P < 0.05) γδTCR+ T-cell population is indicated by an asterisk. Values are expressed as average ± standard error of the mean. Mcs5a, resistant congenic harboring the mammary carcinoma susceptibility locus 5a resistance allele; susc., susceptible congenic control; TCR, T-cell receptor.

Back to article page

Breast Cancer Research

ISSN: 1465-542X

Contact us