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Figure 5 | Breast Cancer Research

Figure 5

From: Dietary fat increases solid tumor growth and metastasis of 4T1 murine mammary carcinoma cells and mortality in obesity-resistant BALB/c mice

Figure 5

Dietary fat alters the protein levels of urokinase-type plasminogen activator (uPA), plasminogen activator inhibitor (PAI)-1, intercellular adhesion molecule (ICAM)-1, and vascular cell adhesion molecule (VCAM)-1 in the lungs of BALB/c mice injected with 4T1 cells. Mice were fed, injected with 4T1 cells, and then killed as described in Figure 1c. Lung lysates were analyzed with Western blotting with the indicated antibodies. Photographs of chemiluminescent detection of the blots are shown. The relative abundance of each band to its own β-actin was quantified, and the control levels were set at 100%. The adjusted mean ± SEM is shown above each blot. *Significantly different from the control group, P < 0.05. MMP, matrix metalloproteinase; TIMP, tissue inhibitor of matrix metalloproteinase.

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