Skip to main content
Figure 8 | Breast Cancer Research

Figure 8

From: Reversal of endocrine resistance in breast cancer: interrelationships among 14-3-3ζ, FOXM1, and a gene signature associated with mitosis

Figure 8

14-3-3ζ status impacts the activation of key signaling proteins. Phosphorylation of human epidermal growth factor receptor 2 (HER2), epidermal growth factor receptor (EGFR), AKT/Protein kinase B (AKT/PKB), and mitogen activated protein kinase (MAPK) was investigated by western blot in tamoxifen-resistant cells following siRNA knockdown or overexpression of 14-3-3ζ and treatment with 1 μM tamoxifen (Tam).

Back to article page

Breast Cancer Research

ISSN: 1465-542X

Contact us