Table 2 Incidence of disease recurrence and deaths according to the detection of CK-19 mRNA-positive circulating tumor cells
CK-19 mRNA | No of patients | Relapses | Â | Deaths | Â | ||
|---|---|---|---|---|---|---|---|
| Â | Â | Yes N (%) | No N (%) | Fisher's Exact test, P | Dead N (%) | Alive N (%) | Fisher's Exact test, P |
Persistently Positive | 99 | 36 (36.4) | 63 (63.6) | P < 0.001 | 24 (24.2) | 75 (75.8) | P = 0.001 |
Persistently Negative | 80 | 9 (11.2) | 71 (88.8) | Â | 5(6.3) | 75 (93.8) | Â |
Positive Turn to negative | 64 | 5 (7.8) | 59 (92.2) | P < 0.001 versus persistently positive | 3 (4.7) | 61 (95.3) | P = 0.001 versus persistently positive |
Negative Turn to positive | 69 | 13 (18.8) | 56 (81.2) | P = 0.016 versus persistently positive | 9 (13.0) | 60 (87.0) | P = 0.079 versus persistently positive |