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Table 1 Correlation of FOXP3 Treg with clinicopathological parameters and CXCL12 expression

From: Recruitment of regulatory T cells is correlated with hypoxia-induced CXCR4 expression, and is associated with poor prognosis in basal-like breast cancers

 

Treg < 15

Treg ≥15

P-value

Tumour size (mm)

   

Median

21.2

23.8

0.571

Tumour grade

  

< 0.001

1

56 (22%)

25 (11%)

 

2

123 (47%)

84 (38%)

 

3

80 (31%)

115 (51%)

 

Nodal status

  

0.062

Negative

154 (59%)

109 (51%)

 

Positive

107 (41%)

107 (49%)

 

ER

  

0.025

Negative

73 (28%)

81 (38%)

 

Positive

189 (72%)

135 (62%)

 

HER2

  

0.002

Negative

238 (97%)

186 (90%)

 

Positive

7 (3%)

20 (10%)

 

CXCL12

  

0.008

Negative

51 (41%)

27 (25%)

 

Positive

74 (59%)

83 (75%)

 

Endocrine Rx

  

0.255

Negative

99 (37%)

72 (32%)

 

Positive

167 (63%)

151 (68%)

 

Chemotherapy

  

0.148

Negative

168 (64%)

127 (57%)

 

Positive

96 (35%)

95 (43%)

 
  1. ER, estrogen receptor; Rx, therapy.