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Table 9 Relative risk of other second cancers* among patients given radiation therapy, by age-at- risk

From: Second malignancies in breast cancer patients following radiotherapy: a study in Florence, Italy

Age-at-risk

RRaunadjusted for chemotherapy and hormonal therapy (95% CIb)

RRaadjusted for chemotherapy and hormonal therapy (95% CIb)

Cases/women with radiotherapy

Cases/women with no radiotherapy

<50

2.12 (0.30, 15.07)

1.64 (0.22, 12.10)

3/569 (0.5%)

2/607 (0.3%)

50 to 64

1.67 (0.71, 3.91)

1.46 (0.62, 3.43)

11/926 (1.2%)

11/1,154 (1.0%)

65+

2.07 (0.98, 4.35)**

2.04 (0.96, 4.35)

15/482 (3.1%)

16/1,022 (1.6%)

  1. * Other second cancers are all second cancers other than contralateral breast cancer and leukaemia.
  2. ** P = 0.055.
  3. a Relative risk is calculated based on a follow-up of five or more years.
  4. b Confidence interval.