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Table 8 Relative risk of other second cancers* among patients given radiation therapy, by age-at- treatment

From: Second malignancies in breast cancer patients following radiotherapy: a study in Florence, Italy

Age-at-treatment

RRaunadjusted for chemotherapy and hormonal therapy (95% CIb)

RRaadjusted for chemotherapy and hormonal therapy (95% CIb)

Cases/women with radiotherapy

Cases/women with no radiotherapy

<50

1.54 (0.60, 3.93)

1.36 (0.53, 3.51)

9/584 (1.5%)

10/632 (1.6%)

50 to 64

2.44 (1.12, 5.30)**

2.36 (1.08, 5.14)**

18/549 (3.3%)

11/687 (1.6%)

65+

0.92 (0.18, 4.66)

0.82 (0.16, 4.13)

2/134 (1.5%)

8/494 (1.6%)

  1. * Other second cancers are all second cancers other than contralateral breast cancer and leukaemia.
  2. ** P <0.05.
  3. a Relative risk is calculated based on a follow-up of five or more years.
  4. b Confidence interval.