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Table 5 Relative risk of all second cancers among patients given radiotherapy, by age-at-risk

From: Second malignancies in breast cancer patients following radiotherapy: a study in Florence, Italy

Age-at-risk (years)

RRaunadjusted for chemotherapy and hormonal therapy (95% CIb)

RRaadjusted for chemotherapy and hormonal therapy (95% CIb)

Cases/women with radiotherapy

Cases/women with no radiotherapy

<50

0.84 (0.37, 2.02)

0.70 (0.29, 1.65)

11/569 (1.9%)

12/607 (2.0%)

50 to 64

1.14 (0.69, 1.87)

1.02 (0.62, 1.68)

28/926 (3.0%)

41/1,154 (3.6%)

65+

1.69 (1.05, 2.73)*

1.65 (1.02, 2.68)*

34/482 (7.1%)

41/1,022 (4.0%)

  1. * P < 0.05.
  2. a Relative risk is calculated based on a follow-up of five or more years.
  3. b Confidence interval.