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Table 11 Relative risk of all second cancers among patients given hormonal therapy, by age-at-treatment

From: Second malignancies in breast cancer patients following radiotherapy: a study in Florence, Italy

Age-at-treatment (years)

Relative Riska(95% CIb)

P-value

Cases/women with hormonal therapy

Cases/women with no hormonal therapy

<50

0.57 (0.17, 1.92)

0.37

3/52 (5.8%)

34/367 (9.3%)

50 to 64

0.85 (0.38, 1.94)

>0.5

8/187 (4.3%)

26/426 (6.1%)

65+

0.52 (0.11, 2.42)

0.40

2/150 (1.3%)

10/333 (3.0%)

ALL

0.70(0.38, 1.30)

0.26

13/150 (8.7%)

70/333 (21.0%)

  1. a Relative risk is calculated based on a follow-up of five or more years.
  2. b Confidence interval.