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Table 2 Sera reacting with MUC1 glycoforms when screened against arrays displaying glycoforms shown in Figure 1B

From: Autoantibodies to aberrantly glycosylated MUC1 in early stage breast cancer are associated with a better prognosis

 

Sera from patients with benign breast disease used to define cut-off

Sera from age-matched healthy females used to define cut-off

 

P< 0.0001

P= 0.0007

 

Breast cancer n (%)

Benign disease n (%)

Breast cancer n (%)

Healthy females n (%)

negative

271 (69)

97 (90)

272 (69)

85 (86)

positive1

124 (31)

11 (10)

123 (31)

14 (14)

strong positive2

97 (24)

8 (7)

80 (20)

7 (7)

  1. 1Sera was defined as positive if it was two standard deviations or higher than the mean fluorescence for at least one feature.
  2. 2 Sera was defined as strong positive if four standard deviations or higher than the mean fluorescence for at least one feature