Figure 2From: Tumor-specific HMG-CoA reductase expression in primary premenopausal breast cancer predicts response to tamoxifenHMG-CoAR mRNA expression is associated with increased recurrence-free survival in tamoxifen-treated breast cancer patients. (a) Mean 3-hydroxy-3-methylglutharyl-coenzyme A reductase (HMG-CoAR) mRNA levels were significantly higher in patients who remained disease-free after tamoxifen treatment. *P < 0.001. (b) Kaplan-Meier using estimates of recurrence-free survival according to HMG-CoAR mRNA expression using mean HMG-CoAR expression as a threshold.Back to article page