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Figure 4 | Breast Cancer Research

Figure 4

From: Prolactin-induced mouse mammary carcinomas model estrogen resistant luminal breast cancer

Figure 4

PRL-induced adenocarcinomas display molecular features of luminal clinical breast tumors. (a-d) RNA from mammary carcinomas that developed in NRL-PRL, MMTV-neu [28], C3(1)-SV40 Tag [29], and transplanted p53-/- (O'Leary and Schuler, manuscript in preparation) models was examined for levels of transcripts comprising the luminal signature [31] by qRT-PCR as described in the Materials and Methods. PRL-induced papillary adenocarcinomas were of diverse ERα status by IHC. Each symbol denotes a distinct tumor. The horizontal bar indicates the mean level for each model.

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