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Table 2 Methylation status and overall survival in primary breast cancer patients using Cox proportional hazard model

From: Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer

 

Patients Φ

(%)

Deaths

HR

95%CI*

P

Cohort 1

      

UM

30

(44.1)

14

1.0(ref)

  

M

38

(55.9)

12

0.53

0.23 to 1.23

0.14

Cohort 2

      

UM

50

(53.8)

21

1.0(ref)

  

M

43

(46.2)

28

0.50

0.23 to 1.08

0.08

  1. Φ Cohort 1 (n = 68) and Cohort 2 (n = 93).
  2. * Adjusted for age, period of diagnosis, ER, PR and p53 status. HR, hazard ratio; UM, unmethylated; M, methylated.