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Figure 2 | Breast Cancer Research

Figure 2

From: Cystatin M loss is associated with the losses of estrogen receptor, progesterone receptor, and HER4 in invasive breast cancer

Figure 2

Relationship between cystatin M loss and the triple-negative status of ER, PR, and HER4. (A) Cystatin M loss occurred at a higher prevalence in the triple-negative IBCs than in other subtypes (P = 0.001). (B) The association between cystatin M loss and triple-negative IBCs was analyzed according to the expression status of HER2. For HER2-negative IBCs, cystatin M loss occurred in 12 (86%) of 14 triple-negative cases and in 46 (53%) of 87 other subtypes (P = 0.02). For HER2-positive IBCs, cystatin M loss was found in 8 (89%) of 9 triple-negative cases and in 33 (51%) of 65 other subtypes (P = 0.04). Triple-negative indicates IBCs with the losses of ER, PR, and HER4.

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Breast Cancer Research

ISSN: 1465-542X

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