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Table 1 Breast cancer patient characteristics

From: CYP2D6 gene variants: association with breast cancer specific survival in a cohort of breast cancer patients from the United Kingdom treated with adjuvant tamoxifen

  

Patients WITH self-reported tamoxifen treatment n= 3155‡

†Patients WITHOUT self-reported tamoxifen treatment n= 3485‡

Median age

 

53

53

Age range

 

24-69

23-69

Tumour size group (cm)

*N/A

913 (13.8%)

1,275 (19.2%)

 

< 2

1,448 (21.8%)

1,380 (20.8%)

 

2-5

710 (10.7%)

751 (11.3%)

 

5+

84 (1.3%)

79 (1.2%)

Grade

1

670 (10.1%)

599 (9%)

 

2

1,487 (22.4%)

1,318 (19.8%)

 

3

560 (8.4%)

1,019 (15.3%)

 

*N/A

438 (6.6%)

549 (8.3%)

Positive nodes

0

1,606 (24.2%)

1,476 (22.2%)

 

1-3

603 (9.1%)

591 (8.9%)

 

4-9

140 (2.1%)

200 (3%)

 

10+

57 (0.9%)

78 (1.2%)

 

*N/A

749 (11.3%)

1,140 (17.2%)

Stage

1

1,624 (24.5%)

1,655 (24.9%)

 

2

1,359 (20.5%)

1,505 (22.7%)

 

3

99 (1.5%)

146 (2.2%)

 

4

28 (0.4%)

50 (0.8%)

 

*N/A

45 (0.7%)

129 (1.9%)

ER

*N/A

959 (14.4%)

1,117 (16.8%)

(oestrogen receptor status)

Negative

207 (3%)

668 (10.1%)

 

Positive

1,989 (30%)

§1,699 (25.6%)

Surgery

Yes

1,982 (29.8%)

1,860 (28%)

 

No

132 (2%)

220 (3.3%)

 

*N/A

1,041 (15.7%)

1,405 (21.2%)

Chemotherapy

Yes

587 (8.8%)

782 (11.8%)

 

No

1,527 (23%)

1,298 (19.5%)

 

*N/A

1,041 (15.7%)

1,405 (21.2%)

Person years follow-up

 

18,860.38

19,189.94

a Number of events

 

312

418

  1. *N/A - Data not available.
  2. §Of 1,699 patients, 1,119 (16.9%) patients received hormone treatment but did not document which type; 3 (0.05%) had combined tamoxifen and aromatase treatment; 232 (3.5%) received aromatase; 341(5.1%) received no hormone treatment; 4 (0.06%) patients had no data available.
  3. †Some patients in this group stated that they received adjuvant hormone treatment but did not document which drug.
  4. ‡Percentages given are from total of 6,640.
  5. aBreast cancer specific deaths.