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Figure 1 | Breast Cancer Research

Figure 1

From: Doxorubicin downregulates cell surface B7-H1 expression and upregulates its nuclear expression in breast cancer cells: role of B7-H1 as an anti-apoptotic molecule

Figure 1

The effect of chemotherapy on B7-H1 expression in breast cancer cell lines. A) Dose dependent effect of chemotherapy in MDA-MB-231 and SKBr3 cells treated for 72 hours (n = 3). B) Representative FACS histograms for the effect of doxorubicin on MDA-MB-231 cells. C) Time dependent effect of doxorubicin (0.8 μg/mL) on MDA-MB-231 cells (n = 3). D) The Effect of different drugs on B7-H1 expression in MDA-MB-231 cells treated for 72 hours (n = 2). Doxo, doxorubicin; DAUN, daunorubicin; and MITO, mitoxantrone.

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