Group | TSH (quartile) | Individuals (n) | Breast cancer cases (n) | Person-years | Incidence/100,000 | All cases | Cases >3 years following Baseline examination | ||
---|---|---|---|---|---|---|---|---|---|
 |  |  |  |  |  | RR (CI: 95%) | RR** (CI: 95%) | RR (CI: 95%) | RR** (CI: 95%) |
All | 1 | 647 | 40 | 11,764 | 340 | 1.00 | 1.00 | 1.00 | 1.00 |
 | 2 | 528 | 42 | 9,517 | 441 | 1.05 (0.70 to 1.58) | 1.07 (0.71 to 1.62) | 1.28 (0.81 to 2.01) | 1.26 (0.80 to 1.97) |
 | 3 | 793 | 55 | 15,829 | 347 | 0.93 (0.62 to 1.41) | 0.94 (0.62 to 1.42) | 1.20 (0.77 to 1.87) | 1.19 (0.76 to 1.85) |
 | 4 | 710 | 36 | 14,521 | 248 | 0.87 (0.55 to 1.37) | 0.80 (0.50 to 1.27) | 0.95 (0.57 to 1.57) | 1.03 (0.62 to 1.69) |
 | P-trend |  |  |  |  | 0.46 | 0.29 | 0.82 | 0.94 |
Premenopausal | 1 | 155 | 10 | 3,170 | 315 | 1.00 | 1.00 | 1.00 | 1.00 |
 | 2 | 221 | 18 | 4,669 | 386 | 1.48 (0.76 to 2.90) | 1.38 (0.69 to 2.77) | 1.91(0.90 to 4.08) | 2.02 (0.97 to 4.23) |
 | 3 | 329 | 28 | 6,869 | 408 | 0.95 (0.48 to 1.87) | 0.94 (0.47 to 1.87) | 1.31(0.62 to 2.79) | 1.30 (0.62 to 2.72) |
 | 4 | 194 | 7 | 4,213 | 166 | 0.81 (0.36 to 1.86) | 0.62 (0.26 to 1.46) | 0.88 (0.35 to 2.21) | 1.11 (0.46 to 2.67) |
 | P-trend |  |  |  |  | 0.42 | 0.20 | 0.64 | 0.91 |
Peri/post-menopausal | 1 | 492 | 30 | 8,593 | 349 | 1.00 | 1.00 | 1.00 | 1.00 |
 | 2 | 307 | 24 | 4,848 | 495 | 0.86 (0.51 to 1.45) | 0.87 (0.51 to 1.47) | 0.93 (0.52 to 1.67) | 0.94 (0.53 to 1.67) |
 | 3 | 464 | 27 | 8,960 | 301 | 0.93 (0.56 to 1.56) | 0.94 (0.56 to 1.58) | 1.13 (0.65 to 1.98) | 1.14 (0.66 to 1.99) |
 | 4 | 516 | 29 | 10,308 | 281 | 0.88 (0.51 to 1.53) | 0.82 (0.47 to 1.43) | 0.89 (0.48 to 1.65) | 0.97 (0.53 to 1.78) |
 | P-trend |  |  |  |  | 0.73 | 0.57 | 0.94 | 0.87 |