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Table 3 Duration and intensity of NSAID¤ use among women with ≥ 10 years of prescription history

From: Prescriptions for selective cyclooxygenase-2 inhibitors, non-selective non-steroidal anti-inflammatory drugs, and risk of breast cancer in a population-based case-control study

Characteristics

Cases*

Controls*

Odds Ratio

95% Confidence Interval

 

N

%

N

%

  

Never/rare

1,188

50

12,714

53

1.00

 

Shorter-term <10 years:

      

   Low Intensity†

317

13

2,997

13

1.09

0.96 to 1.25

   Medium Intensity‡

210

9

2,078

9

1.03

0.88 to 1.20

   High Intensity+

332

14

2,961

12

1.16

1.01 to 1.33

Long-term 10 to </= 15 years:

      

   Low Intensity†

151

6

1,301

5

1.18

0.98 to 1.42

   Medium Intensity‡

81

3

773

3

1.06

0.83 to 1.35

   High Intensity+

88

4

971

4

0.90

0.71 to 1.13

Long-term >15 years:

      

   Low Intensity†

6

0.3

76

0.3

0.80

0.35 to 1.85

   Medium Intensity‡

16

0.7

74

0.3

2.30

1.30 to 4.06

   High Intensity+

10

0.4

96

0.4

1.01

0.52 to 1.97

  1. ¤(sCox-2 inhibitors, aspirin, and non-aspirin non-selective NSAID). * Matched on county of residence and birth year. ^Analyses adjusted for use of hormone replacement therapy, history of rheumatoid arthritis and migraine. † Low intensity was prescription use <25% of duration. ‡ Medium intensity was prescription use >25% but <50% of duration. + High intensity was prescription use >50% of duration.