Figure 4
From: Altered serotonin physiology in human breast cancers favors paradoxical growth and cell survival
Difference in 5-HT receptor isoform gene expression between non-transformed (pHMECs and MCF10A) and breast cancer cells (MCF7, MDA-MB-231 and T47D). (A) Representative RT-PCR reactions (mRNA transcripts) for indicated 5-HT receptors, in cells as indicated at the top. Human brain (hypothalamus) is used as a reference sample for each receptor. For primer information please see Table S1 in Additional data file 1. (B) Densitometric quantification (semi-quantitative) of transcript levels relative to human brain reference samples (100%). Each column represents average with error bars representing ± SEM of at least three independent reactions.