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Table 2 Final model for multivariate analysis of MFS in all patients 1

From: Distinct inherited metastasis susceptibility exists for different breast cancer subtypes: a prognosis study

Characteristic

HR (95% CI)

P

Age (years)

  

   41-55 vs. ≤ 40

0.88 (0.71-1.10)

0.265

   56-70 vs. ≤ 40

0.70 (0.5-0.98)

0.036

   >70 vs. ≤ 40

0.62 (0.43-0.90)

0.013

Menopausal status

  

   Post vs. premenopausal

1.30 (1.01-1.67)

0.045

Lymph nodes involved

  

   1-3 vs. 0

1.80 (1.49-2.18)

< 0.001

   >3 vs. 0

2.73 (2.29-3.25)

< 0.001

Tumor size

  

   pT2 vs. pT1

1.56 (1.32-1.86)

< 0.001

   pT3/4 vs. pT1

1.84 (1.44-2.36)

< 0.001

Grade

  

   Good/moderate vs. poor

0.56 (0.43-0.72)

< 0.001

   Unknown vs. poor

0.91 (0.77-1.06)

0.221

ER

  

   Positive vs. negative

0.79 (0.65-0.96)

0.016

PR

  

   Positive vs. negative

0.82 (0.69-0.98)

0.032

RRP1B rs9306160

  

   CT+TT vs. CC

0.83 (0.71-0.96)

0.012

SIPA1 rs2448490

  

   GG+GA vs. AA

0.85 (0.69-1.05)

0.129

  1. 11725 patients
  2. CI = confidence interval; ER = estrogen receptor; HR = hazard ratio; MFS = metastasis-free survival; PR = progesterone receptor.
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Breast Cancer Research

ISSN: 1465-542X

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