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Table 1 Clinical data of patients

From: Detection and characterization of circulating tumor cells in blood of primary breast cancer patients by RT-PCR and comparison to status of bone marrow disseminated cells

 

Total

CTC-positive

P value

Total

DTC-positive

P value

Total

431

58 (13)

414

107 (24)

  

Tumor size

      

   pT1

285

34 (12)

0.47

274

66 (24)

0.07

   pT2 to pT4*

134

21 (16)

130

40 (31)

  

   bilateral

10

2 (20)

9

0 (0)

  

Nodal status

      

   Node-negative

286

32 (11)

0.04

273

71 (26)

0.92

   Node-positive

142

26 (18)

137

35 (26)

  

Histology

      

   Ductal

349

45 (13)

0.33

337

85 (25)

0.54

   Lobular

65

12 (19)

60

16 (27)

  

   Others

16

1 (6)

16

6 (38)

  

Grading

      

   I

58

6 (10)

0.11

57

14 (25)

0.76

   II

270

32 (12)

255

64 (25)

  

   III

102

20 (20)

101

29 (29)

  

ER status

      

   Negative

60

13 (22)

0.05

57

15 (26)

0.93

   Positive

371

45 (12)

357

92 (26)

  

PR status

      

   Negative

75

17 (23)

0.01

70

25 (36)

0.04

   Positive

356

41 (12)

344

82 (24)

  

HER2

      

   Negative

380

49 (13)

0.35

365

89 (24)

0.06

   Positive

51

9 (18)

49

18 (37)

  

Bone marrow status

      

   Positive

106

20 (19)

0.05

   

   Negative

299

34 (11)

    

Immunhistochemical subtype

      

   (ER-, PR-, HER2-)

26

8 (30)

0.01

23

7 (30)

0.62

   (ER-, PR-, HER2+)

11

0

11

4 (36)

  

   (ER+ and/or PR+)

394

50 (13)

380

96 (25)

  
  1. ER, estrogen receptor; HER2, human epidermal growth factor receptor 2; PR, progesterone receptor.