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Table 5 Significant parameters retained by Cox multivariate analysis in the estrogen receptor positive cases

From: Association of GATA3, P53, Ki67 status and vascular peritumoral invasion are strongly prognostic in luminal breast cancer

N = 378

 

Coefficient

HR

IC95

p-value

Hormonal therapy

no

 

1

  
 

yes

-0.897

0.408

[0.257–0.647]

0.00014

Size

< 25 mm

 

1

  
 

>= 25 mm

0.9

2.46

[1.449–4.175]

0.00085

Scarff-Bloom-Richardson grade

I

 

1

  
 

II–III

0.521

1.68

[0.805–3.522]

0.17

VPI

no

 

1

  
 

yes

0.657

1.93

[1.213–3.068]

0.0055

Lymph node

N-

 

1

  
 

N+

0.68

1.97

[1.208–3.222]

0.0066

BCL2

< 160

 

1

  
 

>= 160

-0.613

0.542

[0.331–0.886]

0.015

Ki67

< 20

 

1

  
 

>= 20

0.641

1.9

[1.167–3.086]

0.0098

P53

0

 

1

  
 

> 0

0.369

1.45

[0.928–2.254]

0.1