Type of therapy | Type of regimen/class of agent | Agents |
---|---|---|
Cytotoxic chemotherapiesa | Single agents | Anthracyclines: doxorubicin (A), epirubicin (E), pegylated liposomal doxorubicin Taxanes: paclitaxel (T), docetaxel (T), nab-paclitaxel Fluoropyrimidines: capecitabine Others: vinorelbine, gemcitabine (G) |
 | Combination chemotherapy | Anthracycline based: CAF/FAC, FEC, AC, EC Taxane-based: T/cisplatin, TG, T/carboplatin, T/capecitabine Anthracycline/taxane: AT Other: CMF |
 | Combinations with targeted or specific anti-VEGF agents | Bevacizumab + paclitaxel |
Endocrine therapies | Aromatase inhibitors | Steroidal (type I): exemestane Nonsteroidal (type II): anastrozole, letrozole |
 | SERMs (anti-oestrogens) | Tamoxifen Toremifene |
 | SERD | Fulvestrant |
 | Progestin | Megestrol acetate |
 | Androgen | Fluoxymesterone |
 | High-dose oestrogen | Ethinylestradiol |