Number of parameters | Akaike information criterion | |||
---|---|---|---|---|
Both BRCA1 and BRCA2 | BRCA1 | BRCA2 | ||
Intercept | 1 | 86.76 | 47.38 | 40.30 |
Sex | 2 | 86.60 | 48.11 | 40.35 |
Proband breast cancer or ovarian cancer | 2 | 87.75 | 48.37 | 41.22 |
Proband breast cancer | 2 | 87.65 | 48.16 | 41.30 |
Proband bilateral breast cancer | 2 | 87.62 | 48.32 | 41.06 |
Proband ovarian cancer | 2 | 85.49 | 46.84 | 40.57 |
Family affected | 2 | 86.19 | 45.05 | 41.29 |
Number of first-degree and second-degree relativesa | 2 | 87.45 | 47.93 | 41.26 |
Total number of family members affecteda | 2 | 85.13 | 47.99 | 38.40 |
Proportion of family members affecteda | 2 | 86.99 | 48.30 | 40.32 |
Total number of tumors (including bilateral) | 2 | 83.58 | 47.93 | 36.24 |
Total number of breast tumors | 2 | 87.46 | 47.82 | 38.90 |
Number of persons with bilateral cancer | 2 | 87.23 | 48.17 | 38.61 |
Total number of ovarian tumors (tnot) | 2 | 74.76 | 38.08 | 38.04 |
Number of persons with ovarian and/or breast tumors (nbot) | 2 | 83.17 | 46.35 | 38.29 |
BRCAPRO score | 2 | 67.36 | 35.90 | 33.74 |
Myriad score | 2 | 69.17 | 36.84 | 34.25 |
Age at diagnosis (diag) | 2 | 82.38 | 42.44 | 40.72 |
BRCAPRO + Myriad | 3 | 66.30 | 35.55 | 33.30 |
BRCAPRO + Myriad + tnot | 4 | 64.58 | 34.32 | - |
BRCAPRO + Myriad + tnot + diag | 5 | 62.46 | 29.10 | - |
BRCAPRO + Myriad + tnot + diag + BRCAPRO:diag | 6 | - | 28.29 | - |
BRCAPRO + tnot + diag + BRCAPRO:diag | 5 | - | 27.51 | - |
BRCAPRO + Myriad + nbot | 4 | - | - | 33.16 |