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Table 6 Odds ratios (95% confidence interval) of prognostic factors among invasive breast cancers according to molecular phenotype, Nurses' Health Study (1976 to 1996)

From: Comparison of molecular phenotypes of ductal carcinoma in situand invasive breast cancer

Tumour type

Luminal A

Luminal B

Her2 type

Basal

Unclassified

 

n

OR

n

OR (95%CI)

n

OR (95%CI)

n

OR (95%CI)

n

OR (95%CI)

Tumour size a,b

          

≤ 2.0 cm

1025

 

54

 

48

 

107

 

57

 

>2.0 cm

537

1.0 (Ref)

55

1.9 (1.3 to 2.8)

68

2.6 (1.8 to 3.9)

119

2.0 (1.5 to 2.7)

44

1.4 (0.9 to 2.1)

Tumour grade a

          

Low/Intermediate

478

 

26

 

21

 

33

 

16

 

High

252

1.0 (Ref)

20

1.4 (0.8 to 2.6)

43

3.6 (2.1 to 6.3)

99

5.3 (3.5 to 8.1)

30

3.4 (1.8 to 6.4)

Nodal status a,b

          

No nodes

1103

 

72

 

61

 

145

 

70

 

Any nodes

547

1.0 (Ref)

44

1.2 (0.8 to 1.7)

67

2.1 (1.5 to 3.1)

100

1.3 (1.0 to 1.7)

40

1.1 (0.7 to 1.6)

Menopausal status

          

Postmenopausal

1289

 

76

 

97

 

187

 

83

 

Premenopausal

334

1.0 (Ref)

35

1.8 (1.2 to 2.7)

27

1.1 (0.7 to 1.7)

51

1.1 (0.8 to 1.5)

25

1.2 (0.7 to 1.8)

  1. aAdjusted for age (five-year categories).bTumour characteristics abstracted from medical pathology reports. CI, confidence interval; OR, odds ratio.
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Breast Cancer Research

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