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Volume 10 Supplement 3

Symposium Mammographicum 2008

Lateral-approach stereotactic vacuum-assisted 10 G breast biopsy using Vacora for indeterminate microcalcifications: results of a single-institution assessment of 172 procedures

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Objective

To report the results of Vacora biopsy under lateral-approach stereotactic guidance.

Methods

Two hundred and fifty procedures were performed in 249 consecutive patients. Specimens were sampled until at least one contained microcalcifications. Surgery was performed whenever malignancy or borderline lesions were found (n = 114). Normal results were mammographically followed up (n = 58). No adequate follow-up was available for 78 procedures.

Results

An average of 4.6 specimens were sampled per procedure. Cancer was diagnosed in 40% of cases: 9.4% invasive ductal carcinomas, 1.2% invasive lobular carcinomas and 29.4% intraductal carcinomas (ductal carcinoma in situ). Borderline lesions were found in 6.1% of cases, mainly atypical ductal hyperplasia (5.7%). The remaining 53.9% of biopsies showed normal or benign findings. The procedure was nondiagnostic in 2% of cases. Vacora biopsy and subsequent surgery were concordant in 89.5% of cases. In 10.5%, biopsy revealed ductal carcinoma in situ while surgery proved invasive carcinoma. In 58 patients who were mammographically followed-up for at least 6 months, no evolution was detected.

Conclusion

Biopsy using Vacora under lateral-approach stereotactic guidance is an easy and intuitive technique for diagnosis of breast microcalcifications. An average of 4.6 specimens per procedure is sufficient to sample representative calcifications for reliable cancer diagnosis.

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Vanherreweghe, E., Mortier, M., Van den Broecke, R. et al. Lateral-approach stereotactic vacuum-assisted 10 G breast biopsy using Vacora for indeterminate microcalcifications: results of a single-institution assessment of 172 procedures. Breast Cancer Res 10, P80 (2008) doi:10.1186/bcr2078

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Keywords

  • Carcinoma
  • Cancer Diagnosis
  • Ductal Carcinoma
  • Normal Result
  • Invasive Carcinoma