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Figure 3 | Breast Cancer Research

Figure 3

From: Differentiation of angiogenic burden in human cancer xenografts using a perfusion-type optical contrast agent (SIDAG)

Figure 3

FRI of different tumour xenografts over time. (a) White light images of different tumour xenografts (as indicated), followed by fluorescence reflectance imaging (FRI) images taken sequentially after application of 2 μmol/kg body weight SIDAG. Note the strong fluorescence signal in the HT1080 (n = 11) fibrosarcomas and in the MDA-MB435 (n = 10) melanomas, whereas the MCF7 (n = 9) and DU4475 (n = 13) adenocarcinomas exhibit only moderate tumour fluorescence. (b) Quantitative data analysis revealed significantly higher contrast to noise ratios (CNRs) for the HT180 and MDA-MB435 xenografts compared with the MCF7 and the DU4475 tumours.

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Breast Cancer Research

ISSN: 1465-542X

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