Table 2 Genotype and allele proportions for breast cancer risk associated with BsmI and Poly(A) genotypes
Genotype | Â | Controlsa (n [%]) | Allele frequency | Casesa (n [%]) | Allele frequency | ORb (95% CI) |
|---|---|---|---|---|---|---|
BsmI | Â | Â | Â | Â | Â | Â |
   All | B/B | 308 (21.7) |  | 345 (20.6) |  | 1.0 (referent) |
| Â | B/b | 539 (37.2) | B 0.41 | 606 (37.2) | B 0.40 | 1.1 (0.9 to 1.3) |
| Â | b/b | 564 (41.0) | b 0.59 | 670 (42.2) | b 0.60 | 1.1 (0.9 to 1.4) |
| Â | any b | 1,103 (78.3) | Â | 1,276 (79.4) | Â | 1.2 (0.9 to 1.3) |
   Caucasian | B/B | 258 (27.3) |  | 278 (24.5) |  | 1.0 (referent) |
| Â | B/b | 371 (38.2) | B 0.46 | 432 (37.9) | B 0.43 | 1.1 (0.9 to 1.4) |
| Â | b/b | 336 (34.5) | b 0.54 | 426 (37.5) | b 0.57 | 1.2 (0.9 to 1.6) |
| Â | any b | 707 (84.4) | Â | 858 (84.8) | Â | 1.2 (0.9 to 1.4) |
   African American | B/B | 50 (11.7) |  | 67 (13.3) |  | 1.0 (referent) |
| Â | B/b | 168 (35.5) | B 0.30 | 174 (36.0) | B 0.32 | 0.9 (0.6 to 1.4) |
| Â | b/b | 228 (52.8) | b 0.70 | 244 (50.7) | b 0.68 | 0.9 (0.5 to 1.3) |
| Â | any b | 390 (88.4) | Â | 406 (86.7) | Â | 0.9 (0.6 to 1.3) |
Poly(A) | Â | Â | Â | Â | Â | Â |
   All | S/S | 176 (12.6) |  | 202 (13.1) |  | 1.0 (referent) |
| Â | L/S | 651 (45.9) | S 0.36 | 713 (44.2) | S 0.35 | 0.9 (0.7 to 1.2) |
| Â | L/L | 575 (41.4) | L 0.64 | 665 (42.7) | L 0.65 | 1.0 (0.8 to 1.3) |
| Â | any L | 1,226 (87.4) | Â | 1,378 (86.9) | Â | 1.0 (0.8 to 1.2) |
   Caucasian | S/S | 149 (15.6) |  | 167 (15.2) |  | 1.0 (referent) |
| Â | L/S | 402 (49.5) | S 0.39 | 532 (46.1) | S 0.38 | 1.0 (0.7 to 1.3) |
| Â | L/L | 354 (34.9) | L 0.61 | 440 (38.7) | L 0.62 | 1.1 (0.8 to 1.5) |
| Â | any L | 836 (72.7) | Â | 972 (75.5) | Â | 1.0 (0. 8 to 1.4) |
   African American | S/S | 27 (6.8) |  | 35 (8.9) |  | 1.0 (referent) |
| Â | L/S | 169 (39.0) | S 0.27 | 181 (40.5) | S 0.28 | 0.8 (0.5 to 1.5) |
| Â | L/L | 221 (54.2) | L 0.73 | 225 (50.6) | L 0.72 | 0.7 (0.4 to 1.3) |
| Â | any L | 396 (93.2) | Â | 418 (91.1) | Â | 0.8 (0.4 to 1.4) |