Cases | Carriers/total probands studied | Controls | Carriers/total probands studied | Odds ratio (95% confidence interval; P value) |
---|---|---|---|---|
Unselected breast cancer (Finland)a [12] | 18/1,918 (0.9%) | Finnish Red Cross blood donorsb | 6/2,501 (0.2%) | 3.91 (1.5–12.1; 0.002)c |
Familial breast cancerd (Finland) [12] | 3/113 (2.7%) | - | 6/2,501 (0.2%) | 11.1 (1.8–52; 0.006)c |
Familial breast cancere (UK) [10] | 10/923 (1.1%) Female breast cancer only 9/908 (1.0%) | 1958 Birth Cohort collection, all aged 48 | 0/1,084 (0%) | 2.3 (1.4–3.9; 0.0025) <50 years: 3.0 (1.4–5.5, NS) >50 years: 1.9 (0.8–3.7, 0.35) |
Strongly familial breast cancer (Canada) [13] | 1/68f (1.5%) | - | - | - |
Breast cancer diagnosed in French-Canadian women <50 years of ageg (Quebec) (the present study) | 2/356 (0.56%) | Newborns, Quebec City, 1996–2003 | 0/6,440 (0%) | -(3.4–∞, 0.0027) |