Circulating Bmi-1 mRNA as a possible prognostic factor for advanced breast cancer patients

Breast Cancer Research

Table 3 Associations between Bmi-1 expression in plasma and clinical-pathological characteristics

Parameter	Number	Mean rank	P value
Age
More than 50 years	66	57.20	NS
Less than 50 years	42	50.26
Histology
Invasive ductal carcinoma	79	52.05	NS
Invasive lobular carcinoma	12	54.08
Other	10	39.00
Vascular invasion
Yes	16	55.69	NS
No	85	50.12
Tumor size
More than 2 cm	54	51.41	NS
Less than 2 cm	44	47.16
Lymph node metastases
Yes	45	47.80	NS
No	52	50.04
Histological grade
I	18	41.94	NS
II	30	37.67
III	33	43.52
Estrogen receptor
Positive	74	47.15	NS
Negative	24	56.75
Progesterone receptor
Positive	73	46.10	0.027
Negative	25	59.44
c-erbB2
Positive	27	34.63	NS
Negative	37	30.95
p53
Positive	26	56.98	0.011
Negative	66	42.37
Ki-67
Positive	67	48.74	NS
Negative	27	44.43
Metastases
Yes	3	58.17	NS
No	95	49.23
Stage
I	26	54.50
II	54	46.59	NS
III	15	49.67
IV	3	57.67

ISSN: 1465-542X