Table 2 The effect of chemotherapy agents on tracer uptake after 3-day treatment
Treatment | Dose (μM) | % PET Tracer uptake reduction | ||||
|---|---|---|---|---|---|---|
FLT | FDG | CHO | MET | ACE | ||
Paclitaxel | 1 | 68 ± 7 | 21 ± 8 | -13 ± 9 | 6 ± 7 | -10 ± 7 |
10 | 69 ± 7 | 17 ± 7 | -6 ± 9 | 7 ± 7 | -10 ± 8 | |
Docetaxel | 1 | 66 ± 6 | 27 ± 7 | -3 ± 7 | 13 ± 6 | 1 ± 5 |
10 | 66 ± 6 | 27 ± 6 | -2 ± 7 | 1 ± 6 | -7 ± 5 | |
Doxorubicin | 1 | 76 ± 5 | 18 ± 5 | 5 ± 6 | -8 ± 5 | 14 ± 5 |
10 | 95 ± 6 | 71 ± 6 | 27 ± 8 | 38 ± 9 | 48 ± 7 | |
Tamoxifen | 1 | 11± 8 | 2 ± 9 | -2 ± 9 | 0 ± 7 | -7 ± 7 |
10 | 28 ± 7 | 22 ± 8 | -2 ± 9 | -7 ± 7 | -45 ± 7 | |
Imatinib | 1 | 7 ± 7 | 3 ± 9 | 4 ± 9 | -6 ± 7 | 2 ± 7 |