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Table 1 Correlation of Ki-67 and mammographic density with demographics and 5-year Gail risk

From: Mammographic density does not correlate with Ki-67 expression or cytomorphology in benign breast cells obtained by random periareolar fine needle aspiration from women at high risk for breast cancer

Variable

Number (%)

Median (interquartile range)

  

Ki-67 (%)

P

Mammographic density (%)

P

Total

344

1.9 (0.4–4.6)

 

37 (21–54)

 

Age (years)

   <48

170

3.1 (1.2–6.0)

<0.001

40 (23–57)

0.035

   >48

174

1.0 (0.2–3.4)

 

35 (19–52)

 

Menopause status

   Pre/peri

162 (47%)

3.3 (1.0–5.8)

<0.001

45 (30–64)

<0.001

   Post

182 (53%)

1.2 (0.2–3.6)

 

32 (16–47)

 

   Post and HRT

114 (33%)

1.2 (0.2–4.0)

0.63

35 (20–49)

0.049

   Post but no HRT

68 (20%)

1.0 (0.2–3.2)

 

24 (11–41)

 

BMI (kg/m2)

   <25

166

2.0 (0.6–4.6)

0.76

49 (34–66)

<0.001

   >25

178

1.8 (0.4–4.4)

 

29 (11–42)

 

5-year Gail risk (%)

   <2.2

167

2.6 (1.0–6.0)

<0.001

43 (28–58)

0.001

   >2.2

176

1.2 (0.2–3.6)

 

33 (17–51)

 

Live birth

   Yes

63

2.2(0.2–5.4)

0.65

45 (32–76)

0.001

   No

281

1.8 (0.6–4.4)

 

36 (30–51)

 

Prior breast cancer

   No

305

2.0 (0.6–4.8)

0.027

38 (22–55)

0.12

   Yes

39

1.0 (0.2–3.0)

 

33 (16–50)

 
  1. The median (range) age was 48 years (20 to 78 years), the median (range) body mass index (BMI) was 25 kg/m2 (17 to 44 kg/m2), and the median (range) 5-year Gail risk was 2.2% (0% to 16%). BMI, body mass index; HRT, hormone replacement treatment.
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Breast Cancer Research

ISSN: 1465-542X

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