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Table 4 Frequencies of CBC patients carrying apathogenic DNA-damage repair pathway mutation

From: Identification of women with an increased risk of developing radiation-induced breast cancer: a case only study

Age (years)

All CBC patients

Previous RT

No RT

Carriers versus non-carriers

 

n

Percentage

n

Percentage

n

Percentage

OR for CBC after RT

95% CI

<40 (n = 91)

22/91

24

19/67

28

3/24

12

2.77

0.74–10.39

40–50 (n = 156)

29/156

18.6

22/102

21.6

7/54

12.9

1.85

0.73–4.65

  1. Results for all contralateral breast cancer (CBC) patients, and patients stratified by previous radiation exposure, are presented, according to age at diagnosis of first primary breast cancer (before the age of 40 years or between 40 and 50 years of age). Odds ratio (OR) and 95% confidence interval (CI) are given for mutation carriers versus non-carriers to develop radiation-associated breast cancer. RT, radiation treatment.