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Table 1 Statistics of key gene ontology categories

From: Inhibitory effects of estrogen receptor beta on specific hormone-responsive gene expression and association with disease outcome in primary breast cancer

Gene function

Percentage total

χ2 p value

E2 + ERβ upregulated

  

   Apoptosis

1.1% (10/893)

0.18590

   Cell cycle

1.5% (13/893)

0.82478

   Cell proliferation

0.4% (4/893)

0.41984

   DNA replication

0.4% (4/893)

0.80576

E2 + ERβ downregulated

  

   Apoptosis

0.4% (3/728)

0.31923

   Cell cycle

2.6% (19/728)

0.02471

   Cell proliferation

0.3% (2/728)

0.91690

   DNA replication

1.4% (10/728)

0.00175

All genes on array

  

   Apoptosis

0.7% (138/18,912)

-

   Cell cycle

1.5% (293/18,912)

-

   Cell proliferation

0.3% (56/18,912)

-

   DNA replication

0.5% (96/18,912)

-

  1. ERβ, estrogen receptor beta.