Diet and body constitution in relation to subgroups of breast cancer defined by tumour grade, proliferation and key cell cycle regulators

Table 5 Means of intake of energy, macronutrients, and fatty acids in relation to specific subgroups of breast cancer

	Energy (Joules/day)	Total fat (g/day)	Energy-adjusted fat (g/day)	SFA (g/day)	Energy-adjusted SFA (g/day)	MUFA (g/day)	Energy-adjusted MUFA (g/day)	PUFA (g/day)	Energy-adjusted PUFA (g/day)
Cyclin D₁ ^a
P value	0.02*	0.007**	0.16	0.002*	0.04*	0.006**	0.13	0.32	0.31
Low	1957	82	81	35	34	29	28	13	13
High	1652	63	76	25	30	22	26	11	13
Cyclin E^b
P value	0.26	0.07	0.09	0.09	0.18	0.08	0.12	0.07	0.15
Low	1937	80	81	34	34	28	28	13	13
High	2123	97	88	42	38	34	31	15	14
Ki67^c
P value	0.029*	0.004**	0.048*	0.019*	0.315	0.004**	0.058	0.003**	0.053
Low	1984	84	82	35	35	29	29	13	13
High	1850	75	79	32	34	26	28	12	12

All analyses are adjusted for age, diet assistant, period, method version and changed dietary habits. Energy adjustment is applied where stated. ^aCyclin D₁ overexpression with nucleus fraction ≥50%. ^bCyclin E overexpression with nucleus fraction ≥50%. ^cHigh proliferation index with nuclear fraction ≥10. *P < 0.05; **P < 0.01. MUFA, monounsaturated fatty acids; PUFA, polyunsaturated fatty acids; SFA, saturated fatty acids.

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