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Table 5 Risk of second primary cancer by time after first primary male breast cancer

From: Risk of second primary cancer in men with breast cancer

 

<1 year

1 to 5 years

>5 years

Cancer site

N

PERYR

OBS

EXP

SIR (95 percent CI)

N

PERYR

OBS

EXP

SIR (95 percent CI)

N

PERYR

OBS

EXP

SIR (95 percent CI)

All, breast included

1,926

1,653.87

42

57.12

0.74 (0.53–0.99)

1,884

4332.66

88

101.51

0.87 (0.70–1.07)

1,796

2,469.34

91

55.92

1.63 (1.31–2.00)

All, breast excluded

1,926

1,655.89

38

57.09

0.67 (0.47–0.91)

1,888

4359.60

81

101.92

0.79 (0.63–0.99)

1,807

2,509.90

82

56.64

1.45 (1.15–1.80)

Prostate

1,926

1,666.28

14

20.83

0.67 (0.37–1.13)

1,912

4450.10

27

37.81

0.71 (0.47–1.04)

1,885

2,683.08

28

21.89

1.28 (0.85–1.85)

Second breast

1,926

1,654.10

4

0.11

34.90 (9.51–89.35)

1,922

4478.09

7

0.21

33.77 (13.58–69.57)

1,915

2,811.43

9

0.12

75.85 (34.68–143.99)

Colorectal

1,926

1,670.38

5

6.23

0.80 (0.26–1.87)

1,921

4524.94

11

11.66

0.94 (0.47–1.69)

1,910

2,825.87

10

7.11

1.41 (0.67–2.59)

Lung and bronchus

1,926

1,672.78

4

9.23

0.43 (0.12–1.11)

1,922

4540.41

6

17.21

0.35 (0.13–0.76)

1,916

2,848.25

13

10.82

1.20 (0.64–2.05)

Bladder

1,926

1,671.12

4

3.73

1.07 (0.29–2.74)

1,922

4534.16

4

6.97

0.57 (0.16–1.47)

1,918

2,821.43

12

4.15

2.89 (1.49–5.05)

Melanomaa

1,454

1,276.50

1

1.48

0.68 (0.02–3.77)

1,453

3491.48

7

2.61

2.68 (1.08–5.53)

1,446

2,199.81

6

1.45

4.15 (1.52–9.02)

Stomach

1,926

1,672.98

2

1.30

1.54 (0.19–5.58)

1,924

4545.53

4

2.43

1.65 (0.45–4.21)

1,920

2,851.61

4

1.50

2.66 (0.72–6.81)

Age (years)

               

   <60

618

531.05

6

5.85

1.02 (0.38–2.23)

612

1445.16

12

12.41

0.89 (0.44–1.59)

600

935.26

23

8.18

2.81 (1.78–4.22)

   60 to 69

547

491.85

7

18.38

0.38 (0.15–0.78)

540

1329.22

36

35.41

1.04 (0.74–1.44)

504

858.89

46

23.64

1.95 (1.42–2.60)

   70+

761

630.97

29

32.89

0.88 (0.59–1.27)

732

1558.27

40

53.69

0.74 (0.53–1.01)

692

675.19

22

24.10

0.91 (0.57–1.38)

  1. Bold numbers indicate that the 95 percent confidence interval (CI) does not include 1.00. aNon-Hispanic whites only. EXP, expected; N, number of subjects; OBS, observed; PERYR, person years at risk; SIR, standardized incidence ratios.