Table 3 Agreement among methods for measuring HER2
Method | Cohen's kappa | Sensitivity | Specificity |
|---|---|---|---|
FISH versus CB11 | 83.0% (SE 5.3%) | 97% | 93% |
HercepTest versus FISH | Â | Â | Â |
   (0–1 versus 2–3) versus FISH | 72.0% (SE 6.2%) | 92% | 87% |
   (0–2 versus 3) versus FISH | 79.2% (SE 6.0%) | 78% | 97% |
HercepTest versus CB11 | Â | Â | Â |
   (0–1 versus 2–3) versus CB11 | 70.0% (SE 6.3%) | 100% | 85% |
   (0–2 versus 3) versus CB11 | 84.2% (SE 5.4%) | 90% | 96% |