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Table 1 Clinicopathological characteristics and gene expression variation of each patient

From: Comparison of gene expression profiles in core biopsies and corresponding surgical breast cancer samples

        

Difference in gene expression between CB and ST (ΔCt [GeneST] – ΔCt [GeneCB])

Patient number

Age

Time between CB and ST (days)

Histology

Tumor diameter (cm)

Grade

Lymph node involvement

Correlation (rs) between paired CB and ST

PAI-1

COX-2

ERBB2

1

68

7

Ductal

3.3

3

Negative

0.97

-0.39

-0.15

-0.08

2

59

8

Ductal

1.8

3

Negative

0.98

-1.68

-0.20

0.52

3

49

21

Ductal

3.3

2

Positive

0.98

-1.19

-1.03

0.62

4

57

13

Ductal

1.1

1

Positive

0.89

-0.63

0.61

-0.02

5

63

14

Ductal

9.0

2

Negative

0.97

-1.41

-1.80

1.40

6

60

21

Ductulo-lobular

2.7

1

Positive

0.98

-1.38

-2.41

0.23

7

80

12

Ductal

3.1

1

Positive

0.95

-2.62

-1.39

0.44

8

81

14

Lobular

2.8

2

Positive

0.94

-3.78

-3.73

0.29

9

34

14

Ductal

1.8

2

Negative

0.95

-3.16

-1.37

0.12

10

68

10

Ductal

0.9

2

Micrometastasis

0.87

-3.57

-7.27

1.01

11

65

16

Lobular

1.9

1

Negative

0.89

-5.16

-0.80

-0.02

12

80

13

Ductal

6.0

3

Positive

0.86

-2.16

-0.20

0.63

13

59

2

Apocrine

2.7

3

Negative

0.98

-1.18

-4.64

-0.27

14

73

12

Lobular

1.9

2

Positive

0.95

-4.60

-3.97

-1.85

15

61

1

Lobular

2.3

2

Positive

0.89

-1.88

-1.61

-0.94

16

73

22

Ductal

1.9

2

Negative

0.98

-1.28

-0.34

0.26

17

58

3

Ductal

9.0

2

Positive

0.96

-0.48

0.26

-0.42

19

68

13

Ductal

1.2

1

Negative

0.97

-2.18

-2.62

0.31

18a

67

11

Ductal

1.5

2

Micrometastasis

NA

NA

NA

NA

20

44

13

Ductulo-lobular

3.2

3

Positive

0.98

-0.12

0.01

0.19

21

71

20

Ductulo-lobular

1.7

3

Negative

0.95

-3.15

-1.69

0.26

22

53

5

Ductal

1.3

2

Negative

0.92

-2.81

-5.48

-0.08

  1. aRNA in the core biopsy (CB) of this patient was degraded and, therefore, omitted from the study. COX, cyclooxygenase; NA, not available; PAI-1, Plasminogen Activator Inhibitor-1; ST, surgical tumor tissue specimen.