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Figure 1 | Breast Cancer Research

Figure 1

From: Estrogen receptor-α and progesterone receptor are expressed in label-retaining mammary epithelial cells that divide asymmetrically and retain their template DNA strands

Figure 1

ER-α-positive and PR-positive epithelial cells are in cycle in during allometric growth. (a) ER-α and [3H]thymidine are detected in mammary tissue. ER-α-positive staining is indicated with black arrowheads and [3H]thymidine incorporation is indicated with red arrowheads. (b) PR and [3H]thymidine are detected in mammary tissue. PR-positive staining is indicated with black arrowheads and [3H]thymidine incorporation is indicated with red arrowheads. (c) Graphical depiction of the number of cells that were double positive for [3H]thymidine incorporation and ER-α or PR (left scale) and the percentage of cells that were ER-α or PR positive within epithelium. Scale bars = 5 μm. ER, estrogen receptor; PR, progesterone receptor.

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Breast Cancer Research

ISSN: 1465-542X

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