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Table 2 Randomised controlled trials of mammography screening: differences in breast cancer incidence between intervention and control arms in the follow-up period

From: Overdiagnosis and overtreatment of breast cancer: Overdiagnosis in randomised controlled trials of breast cancer screening

 

Cumulative incidence of invasive breast cancer (per 1,000 women years)

Cumulative incidence of DCIS (per 1,000 women years)

Cumulative incidence of all breast cancer (invasive + DCIS) (per 1,000 women years)

  

Study

Control group

Absolute excess in intervention arm

95% Cl

Control group

Absolute excess in intervention arm

95% Cl

Control group

Absolute excess in intervention arm

95% Cl

Follow-up (years)

Control group screened

Two County

2.54

-0.13a

-0.29, 0.04

0.12

0.11

0.07, 0.15

2.66

-0.02

-0.19, 0.15

11

Yes

Stockholm

0.85

-0.04

-0.18, 0.10

0.06

0.03

-0.00, 0.07

0.91

-0.03

0.15, 0.14

5

Yes

Goteberg

1.73

-0.17

-0.42, 0.08

0.17

0.05

-0.03, 0.14

1.90

-0.11

-0.38, 0.15

8

Yes

HIP

1.94

0.09a

-0.24, 0.39

No data

No data

No data

1.94

0.07

-0.24, 0.39

5

No

Malmö I

2.12

0.50

0.18, 0.81

0.27

0.23

0.11, 0.36

2.39

0.73

0.39, 1.07

8.8

No

NBSS I

1.68

0.12

-0.08, 0.32

0.09

0.13

0.07, 0.18

1.77

0.25

0.04, 0.46

13

No

NBSS II

2.38

0.04

-0.22, 0.31

0.06

0.21

0.14, 0.28

2.44

0.26

-0.02, 0.54

13

No

Edinburgh

1.93

0.11

-0.15, +0.38

0.05

0.13

0.07, 0.20

1.98

0.25

-0.00, 0.53

10

No

  1. aAll breast cancers. CI, confidence interval; DCIS, ductal carcinoma in situ; HIP, Health Insurance Plan; NBSS, National Breast Screening Study.