Variable | Number of patients | Number of patients with disease (%) | Number of disease-free patients (%) | Mean DFS (months [95% confidence interval]) | P value | Log-rank |
---|---|---|---|---|---|---|
p53 stroma | Â | Â | Â | Â | Â | Â |
   <10% | 24 | 5 (21) | 19 (79) | 173 (142–204) | <0.001 | 10.97 |
   ≥10% | 6 | 5 (83) | 1 (16) | 61 (23–98) |  |  |
HIF-1α stroma |  |  |  |  |  |  |
   <1% | 15 | 3 (20) | 12 (80) | 180 (146–214) | 0.032 | 4.59 |
   ≥1% | 15 | 7 (47) | 8 (53) | 103 (64–142) |  |  |
Ki67 stroma | Â | Â | Â | Â | Â | Â |
   <10% | 16 | 4 (25) | 12 (75) | 176 (145–207) | 0.028 | 4.85 |
   ≥10% | 14 | 6 (43) | 8 (57) | 91 (55–127) |  |  |
Grade | Â | Â | Â | Â | Â | Â |
   Benign | 15 | 4 (27) | 11 (73) | 165 (130–200) | 0.039 | 6.48 |
   Borderline | 5 | 1 (20) | 4 (80) | 140 (86–194) |  |  |
   Malignant | 10 | 5 (50) | 5 (50) | 71 (32–109) |  |  |