Table 1 Comparison of subjects carrying BRCA mutations
From: Changes in body weight and the risk of breast cancer in BRCA1 and BRCA2mutation carriers
Variable | Control subjects (n = 1,073) | Case subjects (n = 1,073) | P a |
|---|---|---|---|
Age (years) at interview, no. (%) | Â | Â | Â |
   ≤ 30 | 17 (1.6) | 26 (2.4) |  |
   31–40 | 219 (20.4) | 242 (22.5) |  |
   41–50 | 415 (38.7) | 386 (36.0) |  |
   51–60 | 277 (25.8) | 264 (24.6) |  |
   ≥ 61 | 145 (13.5) | 155 (14.5) | 0.32 |
Age (years) at interview, mean (SD) | 47.9 (10.6) | 48.6 (10.6) | 0.25 |
Date of birth, mean year | 1951.8 | 1951.2 | 0.14 |
Year of interview, mean (range) | 1999.7 (1995–2004) | 1999.8 (1999–2004) | 0.18 |
Age (years) at diagnosis of breast cancer, no. (%) | Â | Â | Â |
   ≤ 30 | NA | 107 (10.0) |  |
   31–40 |  | 478 (44.5) |  |
   41–50 |  | 371 (34.5) |  |
   ≥ 51 |  | 117 (10.9) |  |
Age (years) at diagnosis of breast cancer, mean (SD) | Â | 39.8 (8.3) | Â |
Mutation, % | Â | Â | Â |
   BRCA1 | 74.3 | 74.3 |  |
   BRCA2 | 25.7 | 25.7 |  |
Parity | Â | Â | Â |
   No. (%) parous | 844 (79.6) | 879 (82.8) | 0.06 |
   Parity, mean (SD) | 1.9 (1.4) | 1.9 (1.3) | 0.18 |
No. (%) who ever used oral contraceptives | 662 (62.6) | 710 (66.8) | 0.04 |
No. (%) who ever smoked | 465 (43.3) | 471 (43.9) | 0.79 |
   Country of residence at time of testing, no. (%) |  |  |  |
   Canada | 420 (39.1) | 420 (39.1) |  |
   Israel | 20 (1.9) | 20 (1.9) |  |
   UK | 8 (0.8) | 8 (0.8) |  |
   Poland | 189 (17.6) | 189 (17.6) |  |
   USA | 436 (40.6) | 436 (40.6) |  |