Table 2 Type II tumor suppressor genes expressed by myoepithelial cells
Myoepithelial tumor suppressor genes | Function | Reference |
|---|---|---|
α-Smooth muscle actin | Cytoskeletal structure; suppress cell growth and motility | [97,98 |
Cytokeratin-5 | Cytoskeletal structure; regulates cell growth | [99] |
α6 integrin | ECM receptor | [100] |
Caveolin-1 | Regulation of cell growth | [101] |
Connexin-43 | Gap junction protein | [102] |
Maspin | Protease inhibitor | [68] |
TIMP-1 | Protease inhibitor | [17] |
Relaxin | Hormone-regulation, cell growth | [103] |
Activin | Hormone regulation | [58] |