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Table 5 Comparison of immunohistochemistry scores for hormone receptors in primary and secondary tumors

From: Phosphorylation of estrogen receptor α serine 167 is predictive of response to endocrine therapy and increases postrelapse survival in metastatic breast cancer

Receptor Primary tumorsa Secondary tumorsa P
ER-α (1D5) 4.9 ± 2.7 3.1 ± 3.2 0.049*
ER-α Ser118 4.9 ± 2.8 7.3 ± 1.6 0.0098*
ER-α Ser167 3.7 ± 1.6 5.5 ± 2.2 0.11
ER-β1 5.5 ± 2.2 7.0 ± 2.0 0.041*
ER-βcx/β2 4.1 ± 2.6 6.1 ± 2.6 0.049*
PR (636) 4.1 ± 3.2 2.9 ± 3.5 0.057
PRA 3.5 ± 2.6 6.1 ± 2.6 0.018*
PRB 3.7 ± 2.4 5.7 ± 2.6 0.027*
  1. aMean ± SD. n = 10. *P <0.05. ER, estrogen receptor; PR(A,B), progresterone receptor (A,B).