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Table 1 Distributions of selected characteristics by case–control status in Caucasians

From: Genotypes and haplotypes of the methyl-CpG-binding domain 2 modify breast cancer risk dependent upon menopausal status

Variable

Cases (n = 393)

Controls (n = 436)

P

Age at menarche (years)

   <11

23 (5.9)

29 (6.7)

 

   11–12

152 (39.2)

168 (38.6)

 

   ≥ 12

213 (54.9)

238 (54.7)

0.907

Menopausal status

   Premenopausal

88 (22.4)

146 (33.5)

 

   Postmenopausal

305 (77.6)

290 (66.5)

0.000

Age at menopause (years)

   <44

76 (25.8)

91 (32.3)

 

   44–49

105 (35.6)

87 (30.9)

 

   ≥ 49

114 (38.6)

104 (36.8)

0.202

Lifetime lactation (months)

   0

242 (61.6)

260 (59.6)

 

   1–5

50 (12.7)

61 (14.0)

 

   6–15

56 (14.3)

59 (13.5)

 

   ≥ 15

45 (11.4)

56 (12.9)

0.853

Family history of breast cancer in first-degree relatives

   Yes

94 (24.0)

98 (22.5)

 

   No

299 (76.0)

338 (77.5)

0.623

Body mass index (kg/m2)

   <25.0

72 (18.3)

77 (17.7)

 

   25.0–29.9

100 (25.5)

110 (25.2)

 

   ≥ 30.0

221 (56.2)

249 (57.1

0.960

Fat intake

   Low

120 (31.0)

141 (33.2)

 

   Medium

132 (34.1)

143 (33.6)

 

   High

135 (34.9)

141 (33.2)

0.786

Cigarette smoking

   Never

169 (43.0)

196 (45.0)

 

   Ever

224 (57.0)

239 (55.0)

0.534

Alcohol consumption

   Never

66 (19.2)

64 (16.9)

 

   Ever

277 (80.8)

315 (83.1)

0.411

Annual income

   Low

126 (39.0)

125 (33.4)

 

   Medium

121 (37.5)

133 (35.6)

 

   High

76 (23.5)

116 (31.0)

0.074

Study site

   New Haven County

266 (67.7)

282 (64.7)

 

   Tolland County

127 (32.3)

154 (35.3)

0.361

Live births

   0

46 (11.95)

66 (15.46)

 

   1–2

200 (51.95)

202 (47.31

 

   ≥ 2

139 (36.10)

159 (37.24)

0.252

  1. Note that missing data for each characteristic were excluded from the analyses. Values are expressed as n (%).