Skip to main content

Table 1 Scoring system used to document cutaneous and subcutaneous reactions in breast cancer patients receiving radiotherapy

From: Early and late skin reactions to radiotherapy for breast cancer and their correlation with radiation-induced DNA damage in lymphocytes

Grade Early reactionsa Late reactionsb
Grade 0 – Highly radioresistant patients No toxicity observed: no erythema, desquamation, or pain Absence of differences between irradiated and nonirradiated skin
Grade 1 – Moderately radioresistant patients Faint, dull, or bright erythema, psilosis, dry desquamation, mild oedema Minimal telangiectasia, slight breast asymmetry, mild hyperpigmentation
Grade 2 – Patients with average radiosensitivity Severe erythema, at least one moist desquamation of small size, moderate oedema Marked telangiectasia, moderate hyperpigmentation, increased density and palpable firmness, mild oedema
Grade 3 – Moderately radiosensitive patients Severe or confluent moist desquamation Partially confluent telangiectasia, severe hyperpigmentation, severe oedema, subcutaneous fibrosis with fixation
Grade 4 – Highly radiosensitive patients Ulceration, haemorrhage Totally confluent telangiectasia, very marked density, retraction and fixation. Major aesthetic sequelae in treated breast
  1. aMorbidity assessed at the end of radiotherapy treatment. bMorbidity assessed at end of 7-year follow-up period