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Table 1 Distribution of NAT2 haplotypes and their gene product acetylator phenotype in 502 breast cancer patients

From: A case-only analysis of the interaction between N-acetyltransferase 2 haplotypes and tobacco smoke in breast cancer etiology

Acetylator phenotype

Haplotype

References

Status

No.

%

  

Fast

24

4.8

NAT2*4/NAT2*4

31–34

Intermediate

158

31.5

All intermediate

14

 

148

93.7

NAT2*4/-

35

 

10

6.3

NAT2*12a/-

 

Slow

320

63.7

All slow

14,33,36

 

81

24.6

NAT2*5b/NAT2*5b

 
 

139

43.4

NAT2*5b/NAT2*6a

 
 

37

11.2

NAT2*5b/-

14,31–33,36

 

43

13.1

NAT2*6a/NAT2*6a

 
 

18

6.1

NAT2*6a/-

14,36,37

 

2

3.3

NAT2*5c/-

 
  1. -, any other haplotype yielding heterozygosity; NAT, N-acetyltransferase.
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Breast Cancer Research

ISSN: 1465-542X

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