Overexpression of β1-chain-containing laminins in capillary basement membranes of human breast cancer and its metastases

Table 4 Expression of different laminin chains in breast tissue blood vessel basement membranes

Sample	Diagnosis	Ln-α1	Ln-α2	Ln-α3	Ln-α5	Ln-β3	Ln-γ1	Ln-γ2
16	Normal	+	-	-	+++	-	+++	-
17	Normal	-	-	-	+++	-	++	-
75	Normal	-	+	-	+++	-	+++	+
77	Normal	-	-	-	++	-	+++	++
67	Normal	-	-	-	+++	-	+++	-
22	DCIS	-	-	-	+++	-	+++	-
38	DCIS	++	++	-	+++	-	++	-
41	DCIS	-	+	-	+++	-	+++	-
50	DCIS	-	++	-	+++	-	+++	-
20	IDC	-	++/+++	-	+++	-	+++	-
30	IDC	-	-	-	+	-	+++	-
28	IDC	-	++	-	+++	-	+++	-
52	IDC	-	-	-	+++	-	+++	-
54	IDC	-	++	-	+++	-	+++	-
121	Metastasis	-	+++	-	+++	-	+++	-
146	Metastasis	-	+++	-	+++	-	+++	-
157	Metastasis	-	++	-	+++	-	+++	-

membranes Ln, laminin; DCIS, ductal carcinoma in situ; IDC, invasive ductal carcinoma. Staining intensity was graded as follows: -, no staining; +, weak staining; ++ distinct staining; +++, bright staining; ++++, very strong staining, /, some vessels in the same sample are in one category and some are in another category.

ISSN: 1465-542X